WORKSHOP

About the Workshop

Metabolism is the unifying feature of life on our planet. Every microbe harbors a series of integrated biochemical reactions encoded in its genome that generate energy and supply the essential building blocks for cell assembly. By examining metabolism, we can understand microbial ecosystems—microbiomes—in mechanistic terms, as the flow of energy and matter between the environment and cells.

The complete set of genome-encoded enzymes offers deep insight into a microbe’s phenotypic landscape. It reveals the organism’s potential food sources, its biochemical pathways, and how these processes work together to build biomass. Within a community, these enzymes also highlight molecular cross-feeding, cooperation, and competition for valuable resources among coexisting metabolic strategies.

In this workshop, we will explore state-of-the-art approaches to reconstruct genome-scale metabolic models from complete genome sequences or metagenome-assembled genomes (MAGs), evaluate their quality, and apply computational methods to interrogate the structure and function of microbiomes from the perspective of reconstructed microbial metabolisms.

Please enroll by filling out the form below and bring a laptop to follow the practicals. The workshop will take place in the Salle Seine. Batiment Lavosier at INRAE/PROSE in Antony

Try to prepare your computer for the workshop by following the first session card below.